Effortless Chicken Tzatziki Casserole Recipe: Mediterranean Flavors Made Easy
Craving a taste of the Mediterranean but short on time? Look no further than this effortless chicken tzatziki casserole recipe! This dump-and-bake wonder transforms simple ingredients into a flavorful and satisfying meal perfect for busy weeknights. Tender chicken bakes to perfection in a creamy, tangy tzatziki sauce, all nestled on a bed of fluffy rice. It’s a healthy, delicious, and customizable casserole that’s ready in under 40 minutes. Say goodbye to complicated cooking and hello to Mediterranean comfort food!
Why you’ll love this Chicken Tzatziki Casserole
This chicken tzatziki casserole is a winner for so many reasons:
- Effortless Prep: Truly a “dump-and-bake” recipe, requiring minimal chopping and mixing.
- Flavorful & Fresh: The combination of creamy tzatziki, savory chicken, and fresh herbs is simply irresistible.
- Customizable: Easily adapt the recipe to your liking by adding your favorite vegetables or adjusting the seasonings.
- Healthy & Satisfying: A great way to enjoy a balanced meal with lean protein, complex carbohydrates, and healthy fats.
- Crowd-Pleaser: Perfect for family dinners, meal prep, or even potlucks.
Ingredients & Substitutions

Here’s what you’ll need to make this delicious casserole:
- Chicken Breasts: 1.5 lbs boneless, skinless chicken breasts, cut into 1-inch pieces. For a variation, try using chicken thighs for a richer flavor.
- Tzatziki Sauce: 1 (16 oz) container. Store-bought is convenient, but homemade tzatziki elevates the dish.
- Cooked Rice: 1 cup. Basmati or jasmine rice work well. You can also use quinoa for a healthier option.
- Feta Cheese: 1/2 cup crumbled. Adds a salty, tangy kick. Goat cheese is a good alternative.
- Fresh Dill: 1/4 cup chopped. Essential for that classic Mediterranean flavor.
- Red Onion: 1/4 cup chopped. Adds a sharp bite. Scallions can be used as a milder substitute.
- Olive Oil: 1 tablespoon. Used for its flavor and healthy fats.
- Lemon Juice: 1 teaspoon. Brightens up the flavors.
- Salt and Pepper: To taste.
- Optional Garnish: Sliced cucumber and cherry tomatoes for a fresh touch.
How to make Chicken Tzatziki Casserole
Follow these simple steps to create your own chicken tzatziki casserole:
- Preheat oven to 375°F (190°C). Lightly grease a 9×13 inch baking dish.
- Spread the cooked rice evenly over the bottom of the baking dish.
- In a bowl, combine the chicken pieces with tzatziki sauce, olive oil, lemon juice, salt, and pepper. Mix well to coat.
- Pour the chicken mixture over the rice in the baking dish, spreading evenly.
- Sprinkle with feta cheese, dill, and red onion.
- Bake for 30 minutes, or until the chicken is cooked through and the cheese is melted and slightly golden.
- Let stand for 5 minutes before serving. Garnish with sliced cucumber and cherry tomatoes, if desired.
Tips for Success
Here are a few tips to ensure your casserole is a culinary triumph:
- Marinate for Maximum Flavor: For an even richer flavor, marinate the chicken in the tzatziki sauce for at least 30 minutes before baking.
- Don’t Overbake: Chicken can dry out easily. Use a meat thermometer to ensure it reaches an internal temperature of 165°F (74°C).
- Add Veggies: Feel free to load up on your favorite vegetables. Bell peppers, zucchini, or spinach are excellent additions. For more inspiration, perhaps consider how these flavors work in this chicken gyros recipe.
- Even Cooking: Ensure the chicken pieces are roughly the same size for even cooking.
- Quality Ingredients: Using high-quality tzatziki and feta cheese makes a big difference in the overall flavor.
Serving Suggestions
This casserole is a complete meal on its own, but here are some serving suggestions to enhance your dining experience:
- Side Salad: A simple Greek salad with crisp lettuce, tomatoes, cucumbers, and olives complements the casserole perfectly.
- Pita Bread: Serve with warm pita bread for dipping into the creamy tzatziki sauce.
- Lemon Wedges: A squeeze of fresh lemon juice brightens the flavors.
- Roasted Vegetables: Consider serving alongside roasted asparagus or broccoli.
Storage & Reheating
Storage: Store leftover chicken tzatziki casserole in an airtight container in the refrigerator for up to 3 days.
Reheating:
- Oven: Reheat in a preheated oven at 350°F (175°C) for 15-20 minutes, or until warmed through.
- Microwave: Reheat individual portions in the microwave for 1-2 minutes, or until heated through. Be sure to check the temperature frequently.
For another delicious Mediterranean-inspired dish, check out this simple mango pudding recipe over at Fork Haven.
FAQ
Q: Can I use pre-cooked chicken?
A: Yes, you can use pre-cooked chicken. Simply reduce the baking time to 15-20 minutes, or until the casserole is heated through.
Q: Can I freeze this casserole?
A: Freezing is not recommended as the tzatziki sauce may separate upon thawing.
Q: Can I use brown rice?
A: Yes, brown rice can be used. Keep in mind that brown rice may require a longer cooking time.
Q: Can I make this casserole ahead of time?
A: Yes, you can assemble the casserole ahead of time and store it in the refrigerator for up to 24 hours before baking. You may need to add a few minutes to the baking time.
Q: Can I add other cheeses?
A: Yes! Halloumi or a mild provolone would also work well.
Enjoy this delicious and easy chicken tzatziki casserole recipe!

Effortless Dump-and-Bake Chicken Tzatziki Casserole
This dump-and-bake Chicken Tzatziki Casserole is the perfect weeknight meal for busy families. Tender chicken breasts bake to perfection in a creamy, tangy tzatziki sauce, all on a bed of fluffy rice. This recipe requires minimal prep work and is incredibly easy to customize with your favorite vegetables. It’s a healthy, satisfying, and delicious meal that’s ready in under 40 minutes. Ideal for meal trains or potlucks. Enjoy the vibrant flavors of the Mediterranean in a comforting casserole form! The cool, refreshing tzatziki perfectly complements the savory chicken, making this a guaranteed crowd-pleaser. No fuss, no mess, just pure flavor!
- Total Time: 40 minutes
- Yield: 6 servings 1x
Ingredients
- 1.5 lbs boneless, skinless chicken breasts, cut into 1-inch pieces
- 1 (16 oz) container tzatziki sauce
- 1 cup cooked rice
- 1/2 cup crumbled feta cheese
- 1/4 cup chopped fresh dill
- 1/4 cup chopped red onion
- 1 tablespoon olive oil
- 1 teaspoon lemon juice
- Salt and pepper to taste
- Optional: sliced cucumber, cherry tomatoes for garnish
Instructions
- Preheat oven to 375°F (190°C). Lightly grease a 9×13 inch baking dish.
- Spread the cooked rice evenly over the bottom of the baking dish.
- In a bowl, combine the chicken pieces with tzatziki sauce, olive oil, lemon juice, salt, and pepper. Mix well to coat.
- Pour the chicken mixture over the rice in the baking dish, spreading evenly.
- Sprinkle with feta cheese, dill, and red onion.
- Bake for 30 minutes, or until the chicken is cooked through and the cheese is melted and slightly golden.
- Let stand for 5 minutes before serving. Garnish with sliced cucumber and cherry tomatoes, if desired.
Notes
For a richer flavor, marinate the chicken in the tzatziki sauce for at least 30 minutes before baking. You can also add other vegetables like bell peppers, zucchini, or spinach to the casserole. Store leftovers in an airtight container in the refrigerator for up to 3 days. Reheat in the oven or microwave until warmed through.
- Prep Time: 10 minutes
- Cook Time: 30 minutes
- Category: Main Course
- Method: Baking
- Cuisine: Mediterranean
Nutrition
- Serving Size: 1 serving
- Calories: 420
- Sugar: 7g
- Sodium: 450mg
- Fat: 20g
- Saturated Fat: 8g
- Unsaturated Fat: 10g
- Trans Fat: 0g
- Carbohydrates: 30g
- Fiber: 2g
- Protein: 30g
- Cholesterol: 90mg
